A New Standard in Sanitary Rupture Disk Design
Pharmaceutical manufacturing demands pressure relief solutions that go beyond conventional engineering. Contamination risks, stringent regulatory requirements, and the need for validated, repeatable performance mean that traditional rupture disk designs often fall short in high-purity environments.
The ZANITARY® Series was developed to address these challenges at the design level. Built on ZOOK’s patent-pending UNIQUE Technology, the ZANITARY® utilizes a material’s natural properties through an exclusive manufacturing process to deliver a rupture disk that is fundamentally different from scored or conventional reverse-acting designs.
The result is a sanitary rupture disk with an inherently smooth process-side surface — free from the indentations, crevices, and dead zones that can harbor contaminants. Every disk meets the demanding geometric requirements of the 3-A Sanitary Standard and is processed through an exclusive passivation operation to ensure an ultra-clean finish as standard.
At A Glance
| Sizes | 1" to 4" (25 mm to 100 mm) | Yes |
|---|---|---|
| Operating Ratio* | Up to 95% | Yes |
| Vacuum | Self-supporting under full vacuum | Yes |
| Compliance | ASME UD, CE, KOSHA, TÜV, 3-A available | Yes |
Why Pharmaceutical Manufacturers Choose ZANITARy®
Ultra-hygienic Design
- 3-A Compliant
- ASME BPE SF1 surface finish ≤20 Ra µin
- Custom passivation process
- Crevice- and dent-free process side
Reliability You Can Validate
- 1,000,000+ cycles (no vacuum)
- 30,000+ cycles (full vacuum)
- Tested at specified temperature
- No chart compensation applied
Designed for High Purity
- CIP/SIP compatible
- FDA plastic-free packaging
- Laser-engraved SS tag
- USP Class VI gaskets
- O₂ cleaning available
Seamless System Integration
- Fits standard sanitary ferrules
- Tri Clover, DIN, ISO compatible
- NovAseptic flange compatible
Trusted for Critical Sanitary Pressure Relief Applications
The ZANITARY® Series provides reliable overpressure protection across a wide range of critical pharmaceutical manufacturing processes. Whether protecting sensitive bioreactors or ensuring safety in high-temperature autoclave environments, ZANITARY® technology is engineered to maintain process integrity without compromising sanitary standards.
- Bioreactors and Fermenters
- Autoclaves
- CIP and SIP Skids and Piping
- Clean Steam Piping
- Sterile Filtration Systems
- Drying, Mixing, and Granulation Equipment
- Process and Transport Vessels
- Lyophilizers (Freeze Dryers)
- Heat Exchangers
- WFI Vessels and Distribution Piping
- Safety Valve Isolation
- Storage Tanks
ZANITARY® Models for Pharmaceutical Pressure Relief
The ZANITARY® Series is available in multiple model configurations to match the specific pressure relief requirements of your pharmaceutical process. Each model builds on the same patent-pending technology platform.
ZAN — High Performance
The ZAN configuration provides a standard operating ratio of up to 95% of the low end of burst tolerance. Ideal for pharmaceutical applications requiring reliable, high-purity sanitary pressure relief with a robust solid metal design and high operating ratios. The ZAN is fully vacuum resistant without the need for separate vacuum support, and is suitable for liquid, gas, and two-phase service.
ZAN95 — Maximum Performance
For pharmaceutical processes that demand the tightest operating window, the ZAN95 configuration delivers an engineered operating ratio of up to 100% of the low end of burst tolerance. Plus Testing is included as standard, providing additional assurance that every disk meets its rated performance. ZAN95 is the preferred choice for critical pharmaceutical applications where system operating pressures must be maximized relative to the relief set point.
What Sets ZANITARY® Apart
The ZANITARY® Series is available in multiple model configurations to match the specific pressure relief requirements of your pharmaceutical process. Each model builds on the same patent-pending technology platform.
Patent-Pending Design
ZOOK’s UNIQUE Technology utilizes a material’s natural properties through an exclusive process – delivering superior fatigue resistance and high-performance pressure relief without conventional scoring or indentation methods.
Ultra-Clean Passivation Finish
After stress relieving, every disk is processed through an eco-friendly passivation operation as standard – not as an add-on. This ensures an ultra-clean surface finish that reduces contamination risk in pharmaceutical process piping.
Paint-Free Laser-Engraved Tagging
The 3-dimensional stainless steel identification tag is permanently laser-engraved with disk information in accordance with ASME and PED standards. No paint or enamel is used, eliminating a potential contamination source in sterile environments.
Eco-Friendly Packaging
Every ZANITARY® disk ships in plastic-free, individually packed, eco-friendly packaging with FDA-compliant coatings – designed for the cleanroom-adjacent environments of pharmaceutical manufacturing.
Welded Cartridge Option
For pharmaceutical facilities requiring a fully sealed, tamper-resistant installation, the ZANITARY® welded cartridge creates hermetic seals upstream and downstream - a true plug-and-play solution that eliminates installation damage risk.
Customize ZANITARY® for Your Pharmaceutical Process
The ZANITARY® Series offers a range of options and accessories to tailor performance to your specific pharmaceutical application requirements.
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Corrosion-Resistant Liners
A process-side PFA Teflon liner provides extra protection from corrosion or viscous process build-up in pharmaceutical applications involving aggressive media. A PEEK liner option is available for applications requiring 3-A compliance.
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Electropolishing
Electropolishing is available in accordance with ASME BPE SF4, providing an enhanced surface finish for pharmaceutical applications requiring the highest level of cleanability and corrosion resistance. Electropolished surfaces further improve cleanability and reduce contamination risk, ideal for the most stringent pharmaceutical and bioprocessing environments.
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Integrated Burst Indication
The ZAN-BI option equips the ZANITARY® disk with ZOOK’s integral burst indicator, providing immediate notification when a disk has ruptured. This is critical for pharmaceutical processes where rapid detection and response to overpressure events is essential for product safety and regulatory compliance.
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Independent Burst Detection
The RDI-S remote sensor provides burst indication for sanitary rupture disk installations. Designed for installation in a sanitary spool on the vent side, the RDI-S offers a simple, reliable method to detect disk activation and support appropriate downstream response within pharmaceutical process systems.
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FDA-Certified Sanitary Gaskets
All gasket materials available for the ZANITARY® Series are certified to FDA USP Class VI. Standard stocked materials include Viton® (FKM), EPDM, Buna (NBR), and Teflon® (PTFE), with Silicone (VMQ) available on request. This broad selection allows pharmaceutical engineers to specify the ideal gasket material for their specific process media and temperature requirements.
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Factory-Verified Performance
Plus Testing to 100% of the low end of the burst tolerance can be specified to ensure no disks will rupture below the rated pressure. This optional verification provides an added layer of assurance for pharmaceutical applications requiring enhanced validation and documentation support.
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Torque-Rite® Clamp Nut
Provides consistent clamp loading through an audible “click” to confirm proper torque. Eliminates over- and under-tightening and installs on standard sanitary clamps without tools or special training.
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Oxygen Service Cleaning
Oxygen service cleaning is available for applications requiring enhanced cleanliness, ensuring disk surfaces are free from contaminants for use in oxygen or high-purity service conditions.
ZANITARY® Brochure
Explore the complete ZANITARY® product overview, technology story, and application guide (PDF).
ZANITARY® Datasheet
Download the full technical datasheet with specifications, pressure ratings, and sizing information (PDF).
Talk to an Engineer
Connect with a ZOOK Pharma application engineer to discuss your specific pharmaceutical pressure relief requirements.
Ready to Upgrade Your Pharmaceutical Pressure Relief?
Connect with a ZOOK Pharma application engineer to discuss how ZANITARY® technology can improve safety, compliance, and reliability in your pharmaceutical manufacturing processes.